Patients with obstructive sleep apnea or sleep-disordered breathing have an increased risk for atrial fibrillation, according to a poster presented at the Cardiometabolic Health Conference.
Irini Youssef, MS, of the department of medicine at SUNY Downstate Medical Center in Brooklyn, New York, and colleagues analyzed data from 19,837 patients with obstructive sleep apnea (OSA) or sleep disordered breathing (SDB) from nine studies. Sample sizes from each trial ranged from 160 patients to 6,841 patients.
OSA was defined as apnea-hypopnea index > 5, respiratory distress index > 30 or 3% oxygen desaturation index > 15.
Patients with OSA had a higher risk for AF compared with the control group (OR = 2.12; 95% CI, 1.845-2.436).
Moderate heterogeneity was observed for the pooled analysis, according to the poster.
“Our study confirms and further strengthens the notion that OSA/SDB populations are at high risk for development of AF, a disease with increased cardiovascular morbidity and mortality,” Youssef and colleagues wrote.