Distinguished Research - Sleep

 Sleep Deprivation and Depression 

  • Date: June 14, 2018
  • Source: Science Daily
  • Summary:  We've all experienced going to bed tired and waking up refreshed, yet how that happens at the molecular level remains a mystery. An international study sheds new light on the biochemistry of sleep need in the brain.

 Sleep Deprivation and Depression 

  • Date: January 21, 2015
  • Source: Sultan Qaboos University Medical Journal
  • Summary:  Al-Maddah et al. reported a significant association between sleep deprivation among medical trainees and depressive indices using the Beck Depression Inventory-2. Using a cross-sectional study design, the authors found that depressive symptoms were more profound with acute rather than chronic sleep deprivation. They attributed the emerging depressive symptoms among medical residents to the acute lack of sleep because of long working hours, but not to the number of on-call nights per week. However, there was no follow-up to ascertain the cause-and-effect relationship between chronic sleep deprivation and depressive indices. 

Connections in the brains of young children strengthen during sleep, CU-Boulder study finds

  • Date: November 20, 2013
  • Source: CU Boulder
  • Summary:  In the new study,  the researchers looked at differences in brain activity during sleep as the children got older and differences in brain activity of each child over a night’s sleep. They found that connections in the brain generally became stronger during sleep as the children aged.  They also found that the strength of the connections between the left and right hemispheres increased by as much as 20 percent over a night’s sleep. 

Persistent Snoring in Preschool Children: Predictors and Behavioral and Developmental Correlates

  • Date: September 2012
  • Source: Official Journal of the American Academy of Pediatrics 
  • Objective: To clarify whether persistent snoring in 2- to 3-year-olds is associated with behavioral and cognitive development, and to identify predictors of transient and persistent snoring.
  • Conclusions: Persistent, loud snoring was associated with higher rates of problem behaviors. These results support routine screening and tracking of snoring, especially in children from low socioeconomic backgrounds; referral for follow-up care of persistent snoring in young children; and encouragement and facilitation of infant breastfeeding.

Sleep deprivation effect on the immune system mirrors physical stress

  • Date: July 2012
  • Source: American Academy of Sleep Medicine
  • Summary: Severe sleep loss jolts the immune system into action, reflecting the same type of immediate response shown during exposure to stress, a new study reports. Researchers compared the white blood cell counts of 15 healthy young men under normal and severely sleep-deprived conditions. The greatest changes were seen in the white blood cells known as granulocytes, which showed a loss of day-night rhythmicity, along with increased numbers, particularly at night.

Sleep and Obesity in Children and Adolescents

  • Date: April 2011
  • Source: Pediatric Clinics of North America
  • Summary: The purpose of the present review is to provide a comprehensive update of current epidemiological studies that have assessed the association between sleep and obesity risk. Data from 29 studies conducted in 16 countries suggest that short sleep is associated with an increased risk for being or becoming overweight/obese or having increased body fat. Late bedtimes were also found to be a risk factor for overweight/obesity. Findings also suggest that changes in eating pathways may lead to increased body fat. Future experimental studies are needed to enhance our understanding of the underlying mechanisms through which sleep may play a role in the development and maintenance of childhood obesity.

Sleep behaviors and sleep quality in children with autism spectrum disorders

  • Date: Dec 2009
  • Source: Sleep 
  • Objectives: (1) Compare sleep behaviors of children with autism spectrum disorders (ASD) with sleep behaviors of typically developing (TD) children using the Children's Sleep Habits Questionnaire (CSHQ); (2) compare sleep quality--defined as mean activity, sleep latency, number of awakenings, sleep efficiency and total sleep time--of the cohort of children with ASD and TD, as measured by 10 nights of actigraphy; and (3) estimate the prevalence of sleep disturbances in the ASD and TD cohorts.
  • Conclusions: The prevalence estimate of 45% for mild sleep disturbances in the TD cohort highlights pediatric sleep debt as a public health problem of concern. The prevalence estimate of 66% for moderate sleep disturbances in the ASD cohort underscores the significant sleep problems that the families of these children face. The predominant sleep disorders in the ASD cohort were behavioral insomnia sleep-onset type and insomnia due to PDD.

A bad night’s sleep linked to suicidal thoughts the following day in people with depression

  • Date: June 2018
  • Source: PsyPost
  • Quote from Researcher: “Suicidal thoughts result from a complex range of multiple different factors. In this research we chose to specifically look at the role of sleep disturbance, because it constitutes a ‘modifiable’ risk factor for suicidal thoughts and attempts. However, most of the research in this area has used cross-sectional, subjective measures which cannot speak to the temporal relationships between sleep disturbance and suicidal thoughts. Furthermore, both sleep and suicidal thoughts vary across short-periods of time. Therefore, we sought to examine the night-to-day, and day-to-night relationships between sleep disturbance and suicidal thoughts.”